Hochviral

According to the World Health Organization, around 40% of all adults are overweight, and around a third of those are obese. Alarmingly, overweight/ obesity is the fifth leading cause of death and considerably increases the risk of getting other diseases, such as diabetes. Unfortunately, curing obesity is not that simple. Since it is a multifactorial disease, lifestyle interventions including exercise and diet are not always sufficient to achieve weight loss. Hence, there is a high interest in the development of safe anti-obesity drugs. In 2009, brown adipose tissue emerged as attractive drug target and the application of targeted nanoparticles could be a novel solution to deliver drugs selectively into adipose tissue in order to avoid side effects. mehr